诺贝尔奖报告：“艾滋病毒/艾滋病研究之初”

老贝

弗朗索瓦兹巴尔-西努西教授，2008年诺贝尔生理或医学奖得主

Nobel Laureate Lecture ：“The early years of HIV/AIDS research”

Prof. Francoise Barré-Sinoussi, Nobel Laureate in Physiology or Medicine in 2008


时间：2009年6月18日（星期四）15点-17点

Time: 15:00-17:00, June 18, 2009, Thursday

地点：上海科技馆，浦东新区世纪大道2000号

Venue: Shanghai Science and Technology Museum

2000 Century Avenue, Pudong New Area, Shanghai


主办单位/ Sponsors:

上海科技馆/Shanghai Science and Technology Museum

上海科普教育发展基金会

上海市科学技术委员会


协办单位/ Organisers:

中国科学院上海巴斯德研究所/Institut Pasteur of Shanghai, CAS

上海巴斯德健康研究基金会/Shanghai Pasteur Health Research Foundation

道达尔集团/Total Group Foundation

法国驻上海总领事馆/General Consulate of France in Shanghai


Abstract:
In the early eighties, clinicians started to observe a new alarming epidemic. In June 1981 in the United States, they first reported a number of cases of Pneumocystis carinii in homosexual men. Subsequently the first cases of what would later be known as AIDS were observed in France. In December 1982, virologists at the Institut Pasteur were contacted by clinicians who wondered if the clinical symtomas they were observing could be due to a retrovirus. They provided the Institut
Pasteur team with a biopsy of lymph node from an AIDS patient and ask the researchers to isolate the etiological agent causing this mysterious disease. Indeed, the isolation of a new human retrovirus first known as LAV, lymphoadenopathy associated virus, was first reported and published in May 1983 in Science. This virus would later become the HIV, human immunodeficiency virus and would be shown as the infectious agent responsible for the AIDS disease.

Today, we have learnt that HIV infection is much more complex than initially thought and the mechanisms leading to AIDS pathogenesis are still not entirely understood. The evolution and progression of the disease caused by HIV is closely linked to a number of determinants of both the virus itself and the host. Indeed each particular path of disease progression is determined by a delicate interplay between viral and host factors. Despite all the progress in diagnosis and treatment, at the end of 2008, 33 million people currently live with HIV, 2.7 million were newly infected and a further 2 million died of AIDS. The research priorities remain to define new strategy for prevention, care and cure against HIV/AIDS.

小老虎

嗯。感觉。。。很专业。似乎去了会听不懂。